Other Supplements and Helps for the Low Oxalate Diet

I’ve seen almost every supplement imaginable recommended on the TLO group (though not always as a help for dealing with oxalates). However, these are the ones recommended by the official documentation in the group (in fact, I should mention that I copied some of these verbatim from that documentation; it’s not my intention to make it sound as if this comes from my own research) and most directly related to oxalates and dumping.

Amino Acids

Arginine: Important for replenishing nitrous oxide that helps to reduce oxidative damage from oxalates.

Taurine: Important for making the bile acid taurocholate, which limits absorption of oxalate; take if stools turn yellow.


Vitamin A: Important for helping to close the leaky gut and important as antioxidant.

Vitamin E: Important as an antioxidant.


There is much talk of probiotics on the TLO board. They are generally regarded as necessary for restoring proper gut function, particularly if there is a past history of antibiotic use. There are two probiotics which are recommended time and again among the folks on the board. They are as follows:

VSL #3: This is a very potent probiotic. It is important to note that the sachet version is four times stronger (has four times as many active organisms) than the capsule version. Note that this is a pretty spendy probiotic. You can sometimes snag a deal on VSL #3 via Amazon (check prices here), but make sure that you communicate with the seller to be sure that they ship it packaged with coolant, especially in the summer – this probiotic needs to be kept cool (refrigeration is recommended). If you just want the most trustworthy source (which is often also the best-priced), go straight to the manufacturer’s site. Some have been able to find this probiotic locally, or have their local CVS keep it in stock for them as well, which may save on shipping.

Another note: Some children with PANDAS have difficulty with this probiotic, as it contains a strep strain. For those who have difficulty with this strep strain, many recommend this probiotic:

Custom Probiotics 11-Strain: This is another strong probiotic. It comes in powder form, so the amount taken is easily adjusted to any quantity, though it also includes adult & child size scoops for accurate measurement of doses. While it is recommended as an alternative to VSL#3, they are not entirely similar in their strains, so please compare carefully before making a purchase decision. Here is a link to the manufacturer’s website, where the probiotic may be purchased.

A Word of Caution About Probiotics

One caution I would extend, based on my own personal experience, is to watch very carefully for negative effects from probiotics, particularly the high-dose ones. Reason being, it is possible to cause an overgrowth of probiotic bacteria in the gut, and this will cause many more problems than it helps. I made the grave mistake of doing this not once but twice, and had a very long and expensive path back to health both times.

The worst part of this is that most people don’t have immediate negative reactions to probiotics. I know in my case it was something that developed over the course of a couple of months, and the process of identifying probiotics as the culprit was made more difficult by dumping symptoms as well as other health issues I had going on at the same time. My personal advice: if you are constipated, you might not want to try probiotics. I realize that some folks swear by them for relieving constipation, so in the end you’ll have to make your own decision. But in my case, the combination of constipation and heavy doses of probiotics really set me back.

Other Recommended Supplements and Their Purposes

Alpha Lipoic Acid (ALA): Works for some, not for others; important antioxidant and can prevent some endogenous production of oxalate.

NAC (N-acetyl cysteine): Important for restoring glutathione that gets depleted by oxalate; sometimes there are negative reactions (such as leaky gut).

Glutathione: Helps restore glutathione; helps reduce metabolism of glycolate to oxalate; helps behavior on diet (meltdowns) for some children.

Citrate (a form of calcium or magnesium): May prevent crystalization of oxalate and may help break down crystals already formed.

Lipase or ox bile: May help if steatorrhea is leading to excess absorption of oxalate.

Co-Q10: another valuable antioxidant.

Non-Supplement Suggestions:

Lemon juice: Helps with digestion when given before eating and may help balance pH issues when acidity is a problem.

Antihistamine: Oxalate may cause histamine release so this counters that. Do not use an antihistamine formula that includes a decongestant.

Bicarbonate: sodium bicarbonate (baking soda) or Alka-Seltzer Gold, can reportedly help with behaviors.

4 Responses to Other Supplements and Helps for the Low Oxalate Diet

  1. Jayne Webb says:

    Hello, my name is Jayne Webb. I am 56 and just found out the reason for my many symptoms for the past 20 years, oxalates. I am thankful for the wealth of information on your site. It seems to me that we have had similar symptoms. Could you tell me the kind of calcium with D that you take and when you take it (with magnesium or after)? Right now I am taking Solaray Cal-Mag Citrate Vegetarian capsules, 1000mg each and Natural Factors B6(pyridoxine HCI) 100mg. I started only taking 2 cal-mags a day. The cal-mags have parsley leaf,watercress leaf, alfalfa leaf and dandelion root, are these good to take or are they high oxalate? How much vitamin E should I start out taking? I have more questions but can’t think of them right now. Hope you do not mind if I ask more later as I think of them? Thanks!

    • admin says:

      Hi Jayne!

      Currently, I do not take vitamin D with calcium; I sometimes do during the winter, but more often I separate them. This just works better for me personally.

      I’m also not taking magnesium right now, but honestly I never paid that much attention to when I took it in relation to calcium. I usually take my supplements with meals, but if I feel a need (for example, if I get obvious symptoms of needing B6), I’ll take supplements on an as-needed basis as well.

      I have noticed the high oxalate ingredients in pretty much all Solaray products. However, I haven’t heard too many people complaining of them giving high oxalate symptoms, so I have to wonder if there’s enough present to cause problems for low oxalate dieters.

      As for how much vitamin E, or any other supplement to start out with, that would be a question for your doctor or other health professional. I can’t really make recommendations, because I’m not even close to qualified. :)

      Have a great week,

  2. Jenny says:


    I have a severely autistic child – I have thought about the VSL product however I have concerns about the presence of strep in the product. Whilst this is a good bacteria in the product, there is reason to believe in the autism community that this strain can cause an onset of P.A.N.D.A.S for those children who are already exhibiting signs of this or have results showing presence of strep. Just wondered if you know anything about this?

    Kind regards

    • admin says:

      Hi Jenny,

      I have heard of this, and if you check out the Probiotics section of this page, you’ll see the Custom Probiotics 11-strain that is often mentioned on the TLO group for exactly this reason.

      Hope this helps!

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